Megaloblastic anaemia in non secretory multiple myeloma: a rare presentation
نویسندگان
چکیده
منابع مشابه
Megaloblastic anaemia in non secretory multiple myeloma: a rare presentation.
A 31-year old army soldier presented with a four day history of fever and malaise. He was a teetotaller and a non-vegetarian. Physical examination was unremarkable There was no lymphadenopathy or organomegaly. Fever subsided spontaneously. Investigations showed pancytopaenia (WBC 2.2 × 103/μl , L:65%, N:19%, platelets 77×103/μl, haemoglobin 10.5 g/dl). MCV was 106.5 fl. Blood picture was typica...
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Multiple Myeloma is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells. It is characterized by a clinical pentad of 1) anemia, 2) a monoclonal protein in the serum or the urine or both, 3) bone leisons and or bone pain, 4) hypercalcemia >11.5g/dl and 5) renal insufficiency. Non secretory multiple myeloma is a rare variant of the classic form of multi...
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The spectrum of plasma cell neoplasm represents indolent conditions like Monoclonal Gammopathy of Undetermined Significance (MGUS) to more aggressive multiple myeloma and plasma cell leukemia. Non-secretory myeloma comprises less than 01% of this spectrum where serum protein electrophoresis and quantitative immunoglobulins remain essentially normal. We are presenting a case report of this rare ...
متن کاملRare case with megaloblastic anaemia.
A nine years old boy presented with history of pallor and anaemia since early infancy along with neural hearing loss responding to empirical multivitamin and folic acid therapy started on basis of blood complete picture showing anaemia and megaloblastic anaemia. On investigation he was diagnosed with Thiamine Responsive Megaloblastic Anaemia, a very rare condition in our settings.
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we report a case of multiple myeloma that presented with anorexia, fatigue, high erythrocyte sedimentation rate, bone marrow plasmacytosis of more than 30%, polyuria,and low urine specific gravity. this unusual presentation was diagnosed as nephrogenic diabetes insipidus secondary to a proximal tubular dysfunction. the tubular functional disturbance appeared to be related to the presence of lam...
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ژورنال
عنوان ژورنال: Ceylon Medical Journal
سال: 2013
ISSN: 2386-1274,0009-0875
DOI: 10.4038/cmj.v58i2.5688